Types of Chemotherapy for Secondary Breast Cancer: Fluorouracil

We are looking at different types of chemotherapy - how you take it and possible side-effects - and then hearing from a patient about their experience. This week it’s Fluorouracil also known as 5FU.

What is Fluorouracil (5FU)?

Fluorouracil  is a chemotherapy drug that slows the growth of cancer cells. It is most often used in combination with other cancer drugs to treat many types of cancer including breast cancer.

How do you take it?

Fluorouracil can be given by intravenous injection into a vein. It can also be given as a drip (infusion) with the drip run through a pump that gives the treatment over a set time. This can be over a few days as a continuous infusion.

What are the side effects?

Common side effects of Fluorouracil can include: 

• Risk of infection - the treatment can reduce the number of white blood cells in your blood
• Bruising and bleeding
• Anaemia (low number of red blood cells)
• Feeling sick
• Diarrhoea
• Sore mouth and throat
• Loss of appetite
• Changes to your taste

If you experience any of these side effects, please discuss with your medical team.