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SBC & Me Date of Diagnosis 14/09/2022 Current Treatment Line Paclitaxel and Phesgo How does SBC effect your life? I am still very early on so I’m still getting use to it all.

The Scottish Medicines Consortium (SMC) has announced that trastuzumab deruxtecan (Enhertu®) has been approved for usage within NHSScotland for metastatic HER2-positive breast cancer patients who have received one or more prior anti-HER2-based regimens. The National Institute for Health and Care Excellence (NICE) approved trastuzumab deruxtecan for this same patient cohort in NHS England & Wales in December 2022.

Can you tell me more about why you chose to fundraise for us? I am a big believer that sometimes the smaller charities often get overlooked and therefore do not get the same funding as some of the larger charities.

Sacituzumab govitecan-hziy (known by the trade name TRODELVY®) was approved for NHS usage in 2022 for secondary TNBC patients, who have had two or more systemic therapies (such as chemotherapies), with at least one of these being for advanced disease. TRODELVY® was approved for this demographic of secondary TNBC patients because a phase 3 clinical trial (known as the ASCENT trial) showed positive patient outcomes.

Make 2nds Count is aware that founder Lisa Fleming has spoken on social media about legal action she has brought against the charity. The charity will not comment about the active tribunal other than to confirm that we refute all aspects of the claim.

SBC & Me How does secondary breast cancer affect your life? I do get exhausted, the tiredness suddenly hits me.

The Food and Drug Administration (FDA) is responsible for approving drugs for disease treatment in America. Typically, before a new cancer drug is approved for usage in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA), which has a separate approval process, the drug will initially get approved for usage in America by the FDA first.

Can you tell me a little about yourself? I'm 25 years old and live in Newcastle Upon Tyne with my boyfriend Jake and our German Shepherd Luna.

SBC & Me Date of diagnosis? Secondary diagnosis, October 2020 Current treatment line?

The Make 2nds Count team, trustees and volunteers attended the Edinburgh Breast Cancer Special Symposium (EBCSS) on Saturday 25th February.The event hasn't been held for several years due to COVID, so there was a lot of interest now that it's finally back face to face. The biennial event brings together scientists, healthcare providers and patients to discuss the latest thinking in breast cancer.

SBC & Me Date of diagnosis? 2021 Current treatment line?

The Northern Ireland Cancer Registry at Queen's University Belfast will conduct this study after receiving funding from the charity Cancer Focus NI. This is the first study of its kind and by gathering information on the number of patients living with secondary breast cancer in NI it will help with the future planning of services that can support the needs of patients.

The government has scrapped the specific NHS England 10-year cancer strategy for a new blended 5-year Major Conditions Strategy. England’s health and social care secretary, Steve Barclay, told the House of Commons on 24 January that the Department of Health and Social Care is currently developing a new 5-year Major Conditions Strategy that will tackle the major conditions that contribute to the burden of disease in England.

SBC & Me Date of diagnosis? March 2017 Current treatment line?

When diagnosed with secondary breast cancer, all of the medical terminologies can be very overwhelming. This three part series of posts will tell you a little bit more about the main classifications of secondary breast cancer that are used to direct medical treatments.